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Carbamic Acid, n-[[[(1,1-Dimethylethoxy)Carbonyl]Amino][[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]Methylene]-, 1,1-Dimethylethyl Ester, [N(Z)]- CAS NO 1143571-96-3


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CAS No.:1143571-96-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Carbamic Acid, n-[[[(1,1-Dimethylethoxy)Carbonyl]Amino][[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]Methylene]-, 1,1-Dimethylethyl Ester, [N(Z)]- is a sophisticated carbamate derivative and a key protected intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for complex molecule construction, particularly in pharmaceutical development. Its primary value lies in its role as a versatile synthon for the introduction of specific amine-protected functionalities. This makes it essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological or cardiovascular pathways.
  • Peptide Mimetic Research: Used in the design and synthesis of peptide analogs and mimetics due to its carbamate-protected amine and aromatic ether structure.
  • Protecting Group Chemistry: Functions as a reagent for introducing the tert-butoxycarbonyl (Boc) protecting group onto amines in complex, multi-step synthetic routes.
  • Agrochemical Synthesis: Employed as an intermediate in the research and development of novel herbicides, fungicides, or plant growth regulators.
  • Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).
  • Chemical Biology Probes: Acts as a starting material for creating labeled probes or inhibitors used in biochemical and cellular assay development.

Basic Information

Item Details
Product Name Carbamic Acid, n-[[[(1,1-Dimethylethoxy)Carbonyl]Amino][[4-[2-(1-Pyrrolidinyl)Ethoxy]Phenyl]Amino]Methylene]-, 1,1-Dimethylethyl Ester, [N(Z)]-
CAS No. 1143571-96-3
Molecular Formula C24H38N4O5
Molecular Weight 462.59 g/mol
Synonyms tert-Butyl N-[(Z)-({[4-[2-(pyrrolidin-1-yl)ethoxy]phenyl]amino})(tert-butoxycarbonylamino)methylene]carbamate; (Z)-tert-Butyl (tert-butoxycarbonyl((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)methylene)carbamate; N-Boc-N'-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)carbamimidic acid tert-butyl ester; CAS 1143571-96-3; Protected carbamimidate intermediate; Boc-protected guanidine derivative.
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Quality Control

Our Carbamic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and cGMP-grade synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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