Description

3-(2-Fluoro-3-Hydroxyphenyl)Pentanoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a carboxylic acid group on a fluorinated phenyl ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for specialty polymers, liquid crystals, and advanced organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags, enzyme inhibitors, and other molecular probes for biochemical research.

Basic Information

Product Name	3-(2-Fluoro-3-Hydroxyphenyl)Pentanoic Acid
CAS No.	1142230-96-3
Molecular Formula	C11H13FO3
Molecular Weight	212.22 g/mol
Synonyms	2-Fluoro-3-(1-ethylpropyl)phenol-5-carboxylic Acid; 3-(2-Fluoro-3-hydroxyphenyl)valeric Acid; 2-Fluoro-3-hydroxyphenylpentanoic Acid; 5-(2-Fluoro-3-hydroxyphenyl)pentanoic Acid; β-(2-Fluoro-3-hydroxyphenyl)valeric Acid; 1142230-96-3; 3-(2-Fluoro-3-hydroxyphenyl)pentanoic acid
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoro-3-Hydroxyphenyl)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and acid chlorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%; Any single unknown impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.