Description

7,8-Difluoro-4-Hydroxyquinoline is a high-purity fluorinated quinoline derivative, a key advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is crucial for constructing complex molecules with specific biological and photophysical properties. This compound is essential for research and development teams in the pharmaceutical, agrochemical, and materials science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of antibiotics, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection products, such as herbicides and fungicides, leveraging the fluorine atoms for enhanced efficacy and stability.
• Material Science Precursor: Serves as a starting material for the development of organic electronic materials, including OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Fluorescent Probe Synthesis: The quinoline core is utilized to construct sensitive fluorescent dyes and probes for biochemical sensing and bioimaging applications.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new fluorination reactions and heterocyclic chemistry.
• Ligand for Metal Complexes: Acts as a chelating agent in coordination chemistry to form metal complexes with potential catalytic or diagnostic applications.

Basic Information

Product Name	7,8-Difluoro-4-Hydroxyquinoline
CAS No.	1142193-11-0
Molecular Formula	C9H5F2NO
Molecular Weight	181.14 g/mol
Synonyms	4-Hydroxy-7,8-difluoroquinoline; 7,8-Difluoro-4-quinolinol; 4-Quinolinol, 7,8-difluoro-; 7,8-Difluoro-4-hydroxy-quinoline; 1142193-11-0; 7,8-Difluoro-4(1H)-quinolinone (tautomer)
EINECS	Contact for details

Quality Control

Our 7,8-Difluoro-4-Hydroxyquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.