Description

2-Amino-2-(4-Ethylphenyl)Acetic Acid Hydrochloride is a high-purity, pharmaceutically relevant organic salt. This compound serves as a critical chiral building block and intermediate in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel APIs, particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides that require specific stereochemistry for efficacy.
• Peptidomimetics Research: Acts as a non-natural amino acid derivative in the design and synthesis of peptide analogs and mimetics for drug discovery.
• Ligand and Catalyst Preparation: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Industrial R&D: A valuable reagent for exploratory organic synthesis and process chemistry development in both academic and industrial settings.

Basic Information

Product Name	2-Amino-2-(4-Ethylphenyl)Acetic Acid Hydrochloride
CAS No.	1141934-66-8
Molecular Formula	C10H13NO2 • HCl
Molecular Weight	215.68 g/mol (Free base: 179.22 g/mol)
Synonyms	(4-Ethylphenyl)glycine hydrochloride; 2-Amino-2-(4-ethylphenyl)ethanoic acid hydrochloride; DL-4-Ethylphenylglycine HCl; p-Ethylphenylglycine hydrochloride; α-Amino-4-ethylbenzeneacetic acid hydrochloride; 2-(4-Ethylphenyl)glycine HCl; Amino(4-ethylphenyl)acetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(4-Ethylphenyl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (or as specified)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.