Description

Sb 290157 Trifluoroacetate Salt is a high-purity, non-racemic chiral compound designed for advanced research and development. This material serves as a critical building block or intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical sector. It is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially within therapeutic areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block in the research and synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Employed in catalytic or stoichiometric reactions to introduce specific stereochemistry into target molecules.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: Fundamental research tool in university and corporate laboratories exploring new synthetic methodologies.

Basic Information

Product Name	Sb 290157 Trifluoroacetate Salt
CAS No.	1140525-25-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SB-290157 Trifluoroacetate; SB290157 TFA Salt; (S)-5-(2,6-Dichloro-benzoyl)-6-(4-fluoro-2-hydroxy-phenyl)-2-(2-hydroxy-ethylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7-one Trifluoroacetate; UNII-7Q2H4A6Q8F; 7Q2H4A6Q8F; SB 290157 (TFA); CHEMBL3186032
EINECS	Contact for details

Quality Control

Our Sb 290157 Trifluoroacetate Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment, to meet the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (by HPLC), and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.