Description

3-((tert-Butoxycarbonylamino)Methyl)-5-Methoxyisonicotinic Acid is a high-purity, protected amino acid derivative and a key pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce protected amino acid functionalities into peptide chains.
• Protecting Group Chemistry: Serves as a reagent where the tert-butoxycarbonyl (Boc) group is required to protect amine functionalities during multi-step synthetic sequences.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of targeted small molecule libraries.
• Bioconjugation: Can be utilized in the development of antibody-drug conjugates (ADCs) and other bioconjugate platforms.
• Chemical Biology Probes: Acts as a precursor for synthesizing chemical probes used to study biological pathways and protein function.

Basic Information

Item	Details
Product Name	3-((tert-Butoxycarbonylamino)Methyl)-5-Methoxyisonicotinic Acid
CAS No.	1138444-21-9
Molecular Formula	C13H18N2O5
Molecular Weight	282.29 g/mol
Synonyms	5-Methoxy-3-[[(tert-butoxycarbonyl)amino]methyl]isonicotinic acid; 3-[(Boc-amino)methyl]-5-methoxyisonicotinic acid; 3-(Boc-aminomethyl)-5-methoxypyridine-4-carboxylic acid; Boc-AMMIA; tert-Butyl N-[(5-methoxy-4-pyridinylcarbonyl)methyl]carbamate; 1138444-21-9; AMMIA-Boc
EINECS	Contact for details

Quality Control

Our 3-((tert-Butoxycarbonylamino)Methyl)-5-Methoxyisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.