Description

2-Bromo-4-(Trifluoromethoxy)Benzonic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its bromine and trifluoromethoxy functional groups. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise structural control for research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry to develop novel ligands and catalysts for cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties imparted by the halogen and fluorinated ether groups.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control in laboratory and production settings.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethoxy)Benzonic Acid
CAS No.	1138331-74-4
Molecular Formula	C8H4BrF3O3
Molecular Weight	285.02 g/mol
Synonyms	2-Bromo-4-(trifluoromethoxy)benzoic Acid; Benzoic acid, 2-bromo-4-(trifluoromethoxy)-; 4-(Trifluoromethoxy)-2-bromobenzoic Acid; 2-Bromo-4-trifluoromethoxybenzoic Acid; α-Bromo-4-(trifluoromethoxy)benzoic Acid; 2-Br-4-OCF3-BA
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethoxy)Benzonic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.