Description

Methyl 4-Amino-2-Fluoro-5-Methoxybenzoate is a high-purity fluorinated benzoate derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring strategically placed amino, fluoro, and methoxy functional groups, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or emissive layer materials in OLED device fabrication.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments with unique optical properties.

Basic Information

Product Name	Methyl 4-Amino-2-Fluoro-5-Methoxybenzoate
CAS No.	1137869-87-4
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	4-Amino-2-fluoro-5-methoxybenzoic acid methyl ester; Methyl 4-amino-2-fluoro-5-methoxybenzoate; Benzoic acid, 4-amino-2-fluoro-5-methoxy-, methyl ester; 2-Fluoro-4-amino-5-methoxybenzoic acid methyl ester; Methyl 2-fluoro-4-amino-5-methoxybenzoate; 4-Amino-2-fluoro-5-methoxy methyl benzoate; 1137869-87-4; MFCD28425044
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-2-Fluoro-5-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.