Description

4-Chloro-6,7-Bis(2-Methoxyethoxy)Quinoline is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinoline-based structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for targeted cancer therapies.
• Kinase Inhibitor Development: Serves as a core scaffold in the research and production of potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency, selectivity, and pharmacokinetic properties.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the efficient, large-scale manufacturing of complex drug molecules.
• Biochemical Tool Compound: Utilized in biochemical assays and as a reference standard for pharmacological profiling in drug discovery pipelines.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	4-Chloro-6,7-Bis(2-Methoxyethoxy)Quinoline
CAS No.	1137579-56-6
Molecular Formula	C₁₆H₂₀ClNO₄
Molecular Weight	325.79 g/mol
Synonyms	4-Chloro-6,7-bis(2-methoxyethoxy)quinoline; 6,7-Bis(2-methoxyethoxy)-4-chloroquinoline; 4-Chloro-6,7-di(2-methoxyethoxy)quinoline; Quinoline, 4-chloro-6,7-bis(2-methoxyethoxy)-; 1137579-56-6; 4-Chloro-6,7-bis(2-methoxy-ethoxy)quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Bis(2-Methoxyethoxy)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP standards for pharmaceutical applications, ensuring supply reliability and traceability for critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.