Description

Ethyl 4-(((2R,3R,4S,5R,6S)-4,5-Bis(Benzo[D][1,3]Dioxol-5-Ylcarbamoyloxy)-2-(Hydroxymethyl)-6-Methoxy-Tetrahydro-2H-Pyran-3-Yloxy)Carbonyl)Benzoate is a complex, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of novel therapeutic agents, particularly those targeting complex biological pathways. It is primarily needed by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in the discovery and process development of new drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), especially for investigational drugs.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a reference standard or a key material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Probe Synthesis: Employed in the creation of specialized molecular probes for investigating enzyme mechanisms or cellular signaling pathways.
• Academic Research: Utilized in university and institutional laboratories for cutting-edge research in organic synthesis and chemical biology.

Basic Information

Product Name	Ethyl 4-(((2R,3R,4S,5R,6S)-4,5-Bis(Benzo[D][1,3]Dioxol-5-Ylcarbamoyloxy)-2-(Hydroxymethyl)-6-Methoxy-Tetrahydro-2H-Pyran-3-Yloxy)Carbonyl)Benzoate
CAS No.	1137359-47-7
Molecular Formula	C33H32N2O14
Molecular Weight	680.62 g/mol
Synonyms	Ethyl 4-(((2R,3R,4S,5R,6S)-4,5-Bis(1,3-benzodioxol-5-ylcarbamoyloxy)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3-yl)oxy)carbonyl)benzoate; Benzoic acid, 4-[[(2R,3R,4S,5R,6S)-4,5-bis[(1,3-benzodioxol-5-ylamino)carbonyl]oxy-2-(hydroxymethyl)-6-methoxy-3-tetrahydro-2H-pyranyl]oxy]carbonyl]-, ethyl ester; Ethyl 4-((4,5-bis(1,3-benzodioxol-5-ylcarbamoyloxy)-2-(hydroxymethyl)-6-methoxy-tetrahydro-2H-pyran-3-yloxy)carbonyl)benzoate; Advanced Glycation Endproduct (AGE) Inhibitor Intermediate; Piperonal-derived glycoside ester.
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality management systems. Every batch is supported by comprehensive analytical data to ensure identity, purity, and consistency for critical research applications. Our standard quality commitment includes HPLC purity ≥95% (with higher grades available), full spectroscopic characterization (NMR, MS, IR), and control of specified impurities. Certificates of Analysis (COA) detailing all test results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and incompatible with strong alkali/organic solvent. Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.