Description

6-Bromo-3-(2,2,2-trifluoroethyl)-4(3H)-quinazolinone is a high-value, halogenated quinazolinone derivative, a crucial scaffold in modern pharmaceutical and agrochemical research. Its core value lies in its unique molecular architecture, which serves as a versatile building block for synthesizing novel compounds with targeted biological activity. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinazolinone core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial research.
• Material Science Precursor: Potential use in the development of specialty chemicals and advanced organic materials due to its halogen and fluorine substituents.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Bromo-3-(2,2,2-trifluoroethyl)-4(3H)-quinazolinone
CAS No.	1135283-30-5
Molecular Formula	C10H6BrF3N2O
Molecular Weight	307.07 g/mol
Synonyms	6-Bromo-3-(2,2,2-trifluoroethyl)quinazolin-4(3H)-one; 4(3H)-Quinazolinone, 6-bromo-3-(2,2,2-trifluoroethyl)-; 6-Bromo-3-(trifluoroethyl)-4(3H)-quinazolinone; 6-Bromo-3-(2,2,2-trifluoroethyl)-4-hydroxyquinazoline; 1135283-30-5; 6-Br-3-TFE-quinazolinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-(2,2,2-trifluoroethyl)-4(3H)-quinazolinone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.