Description

Altanserin Hydrochloride is a high-purity, pharmacologically active compound used in advanced research and development. This chemical is critical for studies targeting specific serotonin receptor pathways, offering researchers a reliable tool for neurological and psychiatric investigations. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on CNS drug discovery.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents.
• Neurological Studies: Used as a selective ligand in receptor binding assays and functional studies to investigate serotonin (5-HT) receptor subtypes, particularly 5-HT2A.
• Preclinical Pharmacology: Employed in *in vitro* and *in vivo* models to study drug mechanisms of action, pharmacokinetics, and efficacy related to CNS disorders.
• Biochemical Assay Development: Acts as a critical component in developing and validating high-throughput screening (HTS) assays for drug discovery pipelines.
• Academic Research: Supports basic science research in universities and institutes exploring neurochemistry, signal transduction, and receptor biology.
• Quality Control & Analytical Testing: Used as an analytical reference standard for method development, validation, and impurity profiling in QC laboratories.

Basic Information

Product Name	Altanserin Hydrochloride
CAS No.	1135280-78-2
Molecular Formula	C22H24FN3O2 • HCl
Molecular Weight	425.91 g/mol
Synonyms	Altanserin HCl; 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one hydrochloride; Altanserin hydrochloride salt; 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2-thioxo-2,3-dihydro-4(1H)-quinazolinone hydrochloride; DU 28853 hydrochloride; DU-28853 hydrochloride
EINECS	Contact for details

Quality Control

Our Altanserin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.