Description

4-[(1R)-1-[[(tert-Butoxy)Carbonyl]Amino]Ethyl]Benzoic Acid is a chiral, Boc-protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This high-purity intermediate is essential for the development of novel pharmaceuticals and bioactive compounds, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, medicinal chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected amino acid building block for solid-phase and solution-phase peptide synthesis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the creation of targeted molecular libraries.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amine functionalities in multi-step syntheses.
• Bioconjugation: The carboxylic acid moiety allows for coupling to other molecules, useful in creating antibody-drug conjugates (ADCs) or probes.
• Chemical Biology: Serves as a precursor for designing enzyme inhibitors or receptor ligands.

Basic Information

Item	Details
Product Name	4-[(1R)-1-[[(tert-Butoxy)Carbonyl]Amino]Ethyl]Benzoic Acid
CAS No.	1134776-30-9
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	(R)-4-(1-((tert-Butoxycarbonyl)amino)ethyl)benzoic acid; (R)-N-Boc-1-(4-Carboxyphenyl)ethylamine; Boc-D-4-Aminomethylbenzoic Acid (related derivative); (R)-N-(tert-Butoxycarbonyl)-1-(4-carboxyphenyl)ethanamine; (1R)-1-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]benzoic acid; BOC-(R)-4-Aminoethylbenzoic Acid; (R)-Boc-Aminoethylbenzoic Acid; 4-[(1R)-1-(Boc-amino)ethyl]benzoic acid
EINECS	Contact for details

Quality Control

Our 4-[(1R)-1-[[(tert-Butoxy)Carbonyl]Amino]Ethyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.