Description

(1S,3Ar,4R,6Ar)-4-(3,5-Dimethoxyphenyl)Tetrahydro-1-(3,4,5-Trimethoxyphenyl)-1H,3H-Furo[3,4-C]Furan is a high-purity, advanced pharmaceutical intermediate characterized by its complex polycyclic furan structure with multiple methoxy substituents. This compound is of significant value for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs), particularly in complex organic synthesis. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the manufacture of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target APIs under current Good Manufacturing Practice (cGMP) standards.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Organic Synthesis Reagent: Acts as a specialized reagent for constructing complex heterocyclic systems in academic and industrial research settings.

Basic Information

Product Name	(1S,3Ar,4R,6Ar)-4-(3,5-Dimethoxyphenyl)Tetrahydro-1-(3,4,5-Trimethoxyphenyl)-1H,3H-Furo[3,4-C]Furan
CAS No.	1134188-26-3
Molecular Formula	C23H26O7
Molecular Weight	414.45 g/mol
Synonyms	1H,3H-Furo[3,4-c]furan, 4-(3,5-dimethoxyphenyl)tetrahydro-1-(3,4,5-trimethoxyphenyl)-, (1S,3aR,4R,6aR)-; (1S,3aR,4R,6aR)-4-(3,5-Dimethoxyphenyl)-1-(3,4,5-trimethoxyphenyl)hexahydrofuro[3,4-c]furan; Tetrahydrofuro[3,4-c]furan derivative (CAS 1134188-26-3); Poly-methoxyphenyl furofuran intermediate; Advanced pharmaceutical building block 1134188-26-3.
EINECS	Contact for details

Quality Control

Our (1S,3Ar,4R,6Ar)-4-(3,5-Dimethoxyphenyl)Tetrahydro-1-(3,4,5-Trimethoxyphenyl)-1H,3H-Furo[3,4-C]Furan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0% (Total impurities ≤ 3.0%)
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.