Description

2-Bromo-1-Methyl-4-(Trifluoromethylsulfonyl)Benzene is a high-value, multi-functional aromatic building block featuring both bromo and triflyl substituents. This compound is essential for advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, where its unique structure enables critical coupling and functionalization reactions. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring sulfonyl or aryl bromide functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactive bromine site for further derivatization.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis, particularly in cross-coupling reactions like Suzuki or Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags due to the bio-orthogonal reactivity of the bromoaryl group.

Basic Information

Product Name	2-Bromo-1-Methyl-4-(Trifluoromethylsulfonyl)Benzene
CAS No.	1133116-35-4
Molecular Formula	C9H6BrF3O2S
Molecular Weight	315.11 g/mol
Synonyms	1-Bromo-2-methyl-5-(trifluoromethylsulfonyl)benzene; 2-Methyl-5-(trifluoromethylsulfonyl)bromobenzene; 4-Bromo-3-methylbenzenesulfonyl trifluoride; α,α,α-Trifluoro-2-methyl-5-bromobenzenesulfonate; 2-Bromo-α,α,α-trifluoro-4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Methyl-4-(Trifluoromethylsulfonyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.