Description

(R)-1-(2,6-Dichlorophenyl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis and research. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, process chemists, and fine chemical manufacturers requiring enantiomerically pure intermediates for scalable production.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs and investigational new drugs.
• Asymmetric Synthesis: Used as a resolving agent or chiral auxiliary in stereoselective chemical reactions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of manufacturing routes for target molecules.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(R)-1-(2,6-Dichlorophenyl)Ethanamine Hydrochloride
CAS No.	1131737-05-7
Molecular Formula	C8H10Cl3N
Molecular Weight	250.53 g/mol
Synonyms	(R)-1-(2,6-Dichlorophenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-2,6-dichlorobenzylamine hydrochloride; (R)-2,6-Dichloro-α-methylbenzylamine hydrochloride; (R)-1-(2,6-Dichlorophenyl)ethylamine hydrochloride; (R)-1-Aminoethyl-2,6-dichlorobenzene hydrochloride; (R)-1-(2,6-Dichlorophenyl)ethanamine HCl; (R)-2,6-DCBA hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(2,6-Dichlorophenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. All products undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.