Description

1-n-Cbz-3-Methylbutane-1,3-Diamine-Hcl is a protected diamine derivative, specifically the hydrochloride salt of a Cbz (carboxybenzyl)-protected amino compound. This product serves as a crucial high-purity building block in advanced organic synthesis, offering a reactive amine handle while providing orthogonal protection for selective deprotection strategies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and complex small molecule libraries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates and bioactive molecules.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected diamine linker or for introducing specific side-chain functionalities.
• Protecting Group Strategy: The Cbz (Z) group allows for selective deprotection under mild hydrogenolytic conditions, enabling multi-step synthetic sequences.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands used in asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1-n-Cbz-3-Methylbutane-1,3-Diamine-Hcl
CAS No.	1131622-25-7
Molecular Formula	C14H23ClN2O2
Molecular Weight	286.80 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3-methylbutane-1,3-diamine hydrochloride; N-Cbz-3-Methyl-1,3-butanediamine hydrochloride; (3-Amino-1-{[(benzyloxy)carbonyl]amino}-3-methylbutyl)ammonium chloride; Z-3-Methyl-1,3-butanediamine hydrochloride; Cbz-3-Methylbutane-1,3-diamine HCl; 1,3-Diamino-3-methylbutane, N1-Cbz, hydrochloride; Benzyl (1-amino-3-methyl-3-aminobutyl)carbamate hydrochloride
EINECS	Contact for details

Quality Control

Our 1-n-Cbz-3-Methylbutane-1,3-Diamine-Hcl is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for demanding research and development applications. All batches are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.