Description

3-Bromo-4-(Difluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its unique halogenated and fluorinated ether substituents. This compound is essential for the synthesis of complex molecules, offering chemists a versatile handle for further derivatization and structural diversification. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a critical precursor in the design and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Used in the synthesis of fluorinated aromatic components for high-performance liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial labs to study new cross-coupling reactions, C-H functionalization, and as a ligand precursor in catalyst design.
• Material Science: Investigated for the development of advanced organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-4-(Difluoromethoxy)Benzoic Acid
CAS No.	1131615-10-5
Molecular Formula	C8H5BrF2O3
Molecular Weight	267.03 g/mol
Synonyms	4-(Difluoromethoxy)-3-bromobenzoic acid; Benzoic acid, 3-bromo-4-(difluoromethoxy)-; 3-Bromo-4-difluoromethoxybenzoic acid; 1131615-10-5; 4-Difluoromethoxy-3-bromobenzoic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Difluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.