Description

JWH 018 2'-Naphthyl Isomer is a synthetic cannabinoid receptor agonist research chemical, specifically the 2'-naphthyl positional isomer of the well-known JWH-018. This compound is of significant interest in pharmacological and biochemical research for studying the structure-activity relationships (SAR) of cannabinoid ligands and their interaction with CB1 and CB2 receptors. It serves as a critical reference standard and intermediate for researchers in medicinal chemistry, forensic analysis, and academic institutions focused on neuropharmacology.

Application

• Pharmacological Research: Used as a reference compound in studies investigating cannabinoid receptor binding affinity, selectivity, and functional activity.
• Medicinal Chemistry: Serves as a key intermediate or analog in the design and synthesis of novel therapeutic agents targeting the endocannabinoid system.
• Forensic Science & Toxicology: Employed as an analytical reference standard for the identification and quantification of synthetic cannabinoids in forensic casework and compliance testing.
• Biochemical Assay Development: Utilized in the development and validation of in vitro screening assays for cannabinoid receptor activity.
• Academic Studies: Provides a precise chemical tool for university and institutional research into the physiological and behavioral effects of cannabinoid analogs.
• Chemical Synthesis: Acts as a specialized building block for the synthesis of more complex, labeled, or derivative compounds for advanced research.

Basic Information

Item	Details
Product Name	JWH 018 2'-Naphthyl Isomer
CAS No.	1131605-25-8
Molecular Formula	C24H23NO
Molecular Weight	341.45 g/mol
Synonyms	1-Pentyl-3-(2-naphthoyl)indole; JWH-018 2'-Naphthyl Isomer; 2'-Naphthoyl isomer of JWH-018; 1-Pentyl-1H-indol-3-yl-(naphthalen-2-yl)methanone; Naphthalen-2-yl(1-pentyl-1H-indol-3-yl)methanone; JWH 018 Naphthyl Isomer; JWH018 2'-Naphthyl Analog
EINECS	Contact for details

Quality Control

Every batch of JWH 018 2'-Naphthyl Isomer is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards for reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.