Description

4-Chloro-6-Cyanoquinoline-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinoline-based heterocyclic structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive quinoline scaffold.
• Organic Synthesis Building Block: Serves as a versatile substrate for further functionalization (e.g., Suzuki coupling, nucleophilic substitution) in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science: Investigated as a potential component in the synthesis of organic electronic materials and ligands for catalysts.

Basic Information

Product Name	4-Chloro-6-Cyanoquinoline-3-Carboxamide
CAS No.	1131604-95-9
Molecular Formula	C11H6ClN3O
Molecular Weight	231.64 g/mol
Synonyms	4-Chloro-6-cyano-3-quinolinecarboxamide; 3-Carbamoyl-4-chloroquinoline-6-carbonitrile; 4-Chloro-6-cyanoquinoline-3-carboxylic acid amide; Quinoline-3-carboxamide, 4-chloro-6-cyano-; 1131604-95-9; 4-Chloro-6-cyano-quinoline-3-carboxylic acid amide; 4-Chloro-6-cyano-3-quinolinecarboxylic acid amide
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Cyanoquinoline-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.