Description

(1R,3S)3-Aminocyclopentacynide is a chiral, non-natural amino acid derivative characterized by its cyclopentane backbone and cyano functional group. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with precise stereochemical control. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Peptidomimetics & Constrained Peptide Design: The rigid cyclopentane scaffold is utilized to introduce conformational constraints into peptide analogs, enhancing metabolic stability and bioavailability.
• Agrochemical Research: Employed in the discovery of new herbicides, fungicides, and insecticides where specific chirality is crucial for biological activity.
• Chemical Biology Probe Development: Used to create labeled or modified probes for studying enzyme mechanisms and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or mechanical properties.

Basic Information

Product Name	(1R,3S)3-Aminocyclopentacynide
CAS No.	1127904-67-9
Molecular Formula	C7H10N2
Molecular Weight	122.17 g/mol
Synonyms	(1R,3S)-3-Aminocyclopentanecarbonitrile; (1R,3S)-3-Amino-1-cyclopentanecarbonitrile; (1R,3S)-3-Aminocyclopentyl cyanide; 3-Aminocyclopentanecarbonitrile (1R,3S)-; (1R,3S)-rel-3-Aminocyclopentanecarbonitrile; Aminocyclopentacynide, (1R,3S)-; (1R,3S)-3-Cyano-cyclopentylamine
EINECS	Contact for details

Quality Control

Our (1R,3S)3-Aminocyclopentacynide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.