Description

Neu5Acalpha2-6Galbeta1-4Glcnacbeta1-2Manalpha1-3(Neu5Acalpha2-3Galbeta1-4Glcnacbeta1-2Manalpha1-6)Manbeta1-4Glcnacbeta1-4Glcnac CAS NO 1125602-44-9 is a complex, high-purity biantennary N-linked oligosaccharide featuring terminal sialic acid (Neu5Ac) residues. This compound is a critical reagent for studying glycan-protein interactions, cell signaling, and immune system modulation. It is essential for researchers and developers in glycobiology, vaccine development, and biopharmaceuticals who require structurally defined glycans for analytical standards, assay development, and drug discovery.

Application

• Glycan Array Development: Used as a high-quality, structurally defined ligand for profiling lectin and antibody specificity.
• Biopharmaceutical Research: Serves as a critical standard and reference material for analyzing the glycosylation patterns of therapeutic proteins, including monoclonal antibodies.
• Enzyme Substrate & Inhibitor Studies: Acts as a substrate for sialidases, sialyltransferases, and other glycosyltransferases to study enzyme kinetics and screen for inhibitors.
• Cell Biology & Immunology: Employed to investigate the role of sialylated glycans in cell adhesion, pathogen recognition, and immune cell regulation.
• Diagnostic Assay Development: Utilized in the development of sensitive immunoassays and biosensors for detecting glycan-binding proteins.
• Vaccine Adjuvant Research: Explored for its immunomodulatory properties in the design of novel vaccine formulations and conjugate vaccines.
• Mass Spectrometry Calibration: Provides a precise molecular weight standard for the calibration of mass spectrometers in glycomics and proteomics workflows.

Basic Information

Product Name	Neu5Acalpha2-6Galbeta1-4Glcnacbeta1-2Manalpha1-3(Neu5Acalpha2-3Galbeta1-4Glcnacbeta1-2Manalpha1-6)Manbeta1-4Glcnacbeta1-4Glcnac
CAS No.	1125602-44-9
Molecular Formula	C94H155N7O72
Molecular Weight	2595.2 g/mol (theoretical)
Synonyms	Biantennary Disialylated N-Glycan; Disialylated Biantennary Complex-type Oligosaccharide; A2G2S2; Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3[Neu5Acα2-3Galβ1-4GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc; N-Glycan, Bi-2,6/2,3; Sialyl N-Glycan; Glycan Standard A2G2S2; Asialo, Disialo Biantennary N-Linked Oligosaccharide
EINECS	Contact for details

Quality Control

Every batch of our oligosaccharides is produced and analyzed under stringent conditions to ensure structural fidelity and high purity, critical for research reproducibility. Quality is verified by a combination of advanced analytical techniques including HPLC, Mass Spectrometry (MS/MS), and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (MS)	Consistent with molecular structure
Identification (NMR)	Consistent with molecular structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.