Description

2-(Acetylamino)-2-[[8-(Acetyloxy)-3-Quinolinyl]Methyl]Propanedioic Acid 1,3-Diethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based molecular structure. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, offering researchers precise control over molecular architecture. It is primarily needed by R&D and process development teams within the pharmaceutical, biotechnology, and fine chemical sectors engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and anti-infective research.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Research & Development (R&D): Essential for academic and industrial laboratories exploring novel heterocyclic compounds and their biological activities.
• Process Chemistry Scale-Up: Employed in optimizing synthetic routes from milligram to kilogram scale for preclinical and clinical trial material production.
• Fine Chemical Production: Utilized in the manufacture of specialized, high-value chemicals for advanced material science applications.

Basic Information

Product Name	2-(Acetylamino)-2-[[8-(Acetyloxy)-3-Quinolinyl]Methyl]Propanedioic Acid 1,3-Diethyl Ester
CAS No.	1123191-91-2
Molecular Formula	C22H24N2O7
Molecular Weight	428.44 g/mol
Synonyms	1,3-Diethyl 2-(acetylamino)-2-[[8-(acetyloxy)-3-quinolinyl]methyl]propanedioate; Propanedioic acid, 2-(acetylamino)-2-[[8-(acetyloxy)-3-quinolinyl]methyl]-, 1,3-diethyl ester; Diethyl (acetylamino)((8-acetoxyquinolin-3-yl)methyl)malonate; (Acetylamino)((8-acetoxyquinolin-3-yl)methyl)malonic acid diethyl ester; CAS 1123191-91-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed to confirm identity, purity, and consistency. Specifications are aligned with the requirements for advanced pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request and document key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.