Description

T-Butyl 6-Bromo-3,4-Dihydro-2H-Quinoline-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core structure. This compound is a critical building block in modern organic synthesis, enabling the construction of complex molecules with high precision and yield. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with specific biological activity.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized quinoline moieties into larger molecular architectures.
• Material Science Research: Investigated as a component in the creation of organic semiconductors and light-emitting materials due to its conjugated system.
• Chemical Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	T-Butyl 6-Bromo-3,4-Dihydro-2H-Quinoline-1-Carboxylate
CAS No.	1123169-45-8
Molecular Formula	C₁₄H₁₆BrNO₂
Molecular Weight	310.19 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydroquinoline-1-carboxylic acid tert-butyl ester; tert-Butyl 6-bromo-1,2,3,4-tetrahydroquinoline-1-carboxylate; 6-Bromo-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester; 1-Boc-6-bromo-1,2,3,4-tetrahydroquinoline; T-Butyl 6-Bromo-1,2,3,4-Tetrahydroquinoline-1-Carboxylate; 6-Bromo-N-Boc-1,2,3,4-tetrahydroquinoline; 1123169-45-8; TB6BDQC
EINECS	Contact for details

Quality Control

Our T-Butyl 6-Bromo-3,4-Dihydro-2H-Quinoline-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.