Description

1-(Hydroxymethyl)Cyclobutanecarboxamide (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutane carboxamide structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, including potential antiviral and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for clinical research and development.
• Antiviral Drug Research: Used in the development of new therapeutic compounds targeting specific viral enzymes and replication mechanisms.
• CNS Drug Discovery: Serves as a precursor in the creation of potential neuroactive compounds for treating neurological disorders.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry & Scale-Up: Utilized in the development and optimization of scalable synthetic routes for new chemical entities (NCEs).
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	1-(Hydroxymethyl)Cyclobutanecarboxamide (Saltdata: Free)
CAS No.	1123169-19-6
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	Cyclobutanecarboxamide, 1-(hydroxymethyl)-; 1-(Hydroxymethyl)cyclobutanecarboxylic acid amide; (1-(Hydroxymethyl)cyclobutyl)formamide; 1-(Aminocarbonyl)cyclobutylmethanol; 1-Carbamoylcyclobutylmethanol; 1123169-19-6 (CAS); Cyclobutane-1-carboxamide, 1-(hydroxymethyl)- (IUPAC)
EINECS	Contact for details

Quality Control

Our 1-(Hydroxymethyl)Cyclobutanecarboxamide (Saltdata: Free) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.