Description

1-Bromo-2-Ethoxy-3,4-Difluorobenzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which provides a versatile handle for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the difluoro and bromo substituents for bioactivity.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing complex, fluorinated aromatic scaffolds.

Basic Information

Product Name	1-Bromo-2-Ethoxy-3,4-Difluorobenzene
CAS No.	1122410-43-8
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	2-Bromo-1-ethoxy-3,4-difluorobenzene; 3,4-Difluoro-2-bromo-1-ethoxybenzene; 1-Ethoxy-2-bromo-3,4-difluorobenzene; Benzene, 1-bromo-2-ethoxy-3,4-difluoro-; 1122410-43-8; 2-Bromo-3,4-difluorophenetole
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Ethoxy-3,4-Difluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.