Description

S-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-[1,1'-Binaphthalene]-2,2'-Diol is a high-purity, chiral binaphthol derivative, specifically the S-enantiomer, valued for its role as a sophisticated ligand and building block in asymmetric synthesis. Its importance lies in its ability to induce high enantioselectivity in catalytic reactions, which is critical for producing single-enantiomer pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance chiral auxiliaries.

Application

This specialized chiral ligand is utilized in a variety of advanced chemical synthesis applications:

• As a key ligand in asymmetric catalysis, including hydrogenation, Diels-Alder, and aldol reactions.
• A crucial chiral building block for the synthesis of pharmaceutical intermediates requiring high optical purity.
• In the development of novel organocatalysts and metal-organic frameworks (MOFs).
• For research into chiral stationary phases used in chromatographic separation techniques.
• In the synthesis of advanced materials with specific optical or electronic properties.
• As a reference standard for analytical method development and quality control in chiral chemistry.

Basic Information

Product Name	S-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	1121764-50-8
Molecular Formula	C40H44O2
Molecular Weight	556.78 g/mol
Synonyms	(S)-H8-BINOL-(3,3')-Mes; (S)-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthalene-2,2'-Diol; (S)-3,3'-Dimesityl-H8-BINOL; S-3,3'-Bis(2,4,6-Trimethylphenyl)-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol; (S)-H8-3,3'-Dimesityl-BINOL; S-Octahydro-Dimesityl-BINOL; S-H8-DMB; S-Chiral Binaphthol Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral compound adheres to stringent quality control protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing purity, chiral purity, and full analytical data are provided with every shipment to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (S-enantiomer)
Melting Point	Contact for details
Specific Rotation	Provided on COA
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.