Description

5-Bromo-2-(Trifluoromethyl)Phenol is a versatile halogenated phenol derivative, distinguished by its bromine and trifluoromethyl substituents which impart unique electronic and steric properties. This compound is a critical high-purity building block in advanced organic synthesis, enabling the development of complex molecules with tailored functionality. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the phenol and halogenated aryl structure.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis, where the electron-withdrawing trifluoromethyl group can fine-tune metal center reactivity.
• Material Science Monomer: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its ability to influence molecular packing and electronic properties.
• Chemical Research & Development: A valuable reagent for method development, structure-activity relationship (SAR) studies, and exploring new reaction pathways in academic and industrial labs.

Basic Information

Item	Detail
Product Name	5-Bromo-2-(Trifluoromethyl)Phenol
CAS No.	1121585-15-6
Molecular Formula	C7H4BrF3O
Molecular Weight	241.01 g/mol
Synonyms	2-Hydroxy-5-bromobenzotrifluoride; 5-Bromo-α,α,α-trifluoro-o-cresol; 5-Bromo-2-(trifluoromethyl)benzenol; 2-Trifluoromethyl-5-bromophenol; 5-Bromo-α,α,α-trifluoro-2-cresol; 5-Bromo-2-hydroxybenzotrifluoride; 5-Bromo-α,α,α-trifluoro-o-hydroxy toluene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. The container must be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.