Description

(S)-n-((1S,2S)-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Ureido)Cyclohexyl)-2-Methylpropane-2-Sulfinamide is a high-purity chiral sulfinamide derivative, a critical building block in modern asymmetric synthesis. Its value lies in its role as a sophisticated ligand or intermediate for constructing complex, enantiomerically pure molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and researchers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity chiral auxiliaries to drive innovation in active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in oncology and central nervous system (CNS) drug discovery.
• Asymmetric Catalyst Ligand: Serves as a precursor or component in chiral catalyst systems for enantioselective transformations, such as additions or reductions.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.
• Chemical Biology Probe Development: Employed in the creation of selective molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-up: Supports route scouting and optimization from milligram to kilogram scale for clinical trial material (CTM) production.
• Academic & Institutional Research: A valuable reagent for methodology development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(S)-n-((1S,2S)-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Ureido)Cyclohexyl)-2-Methylpropane-2-Sulfinamide
CAS No.	1120500-27-7
Molecular Formula	C19H25F6N3O2S
Molecular Weight	473.48 g/mol
Synonyms	(S)-N-((1S,2S)-2-(3-(3,5-Bis(trifluoromethyl)phenyl)ureido)cyclohexyl)-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinamide, N-[(1S,2S)-2-[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]cyclohexyl]-; Chiral Cyclohexyl Urea Sulfinamide; (S)-2-Methyl-2-propanesulfinamide, N-[(1S,2S)-2-[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]cyclohexyl]-; CAS 1120500-27-7; BTRFS Ligand Intermediate; tert-Butylsulfinyl Urea Derivative
EINECS	Contact for details

Quality Control

Our (S)-n-((1S,2S)-2-(3-(3,5-Bis(Trifluoromethyl)Phenyl)Ureido)Cyclohexyl)-2-Methylpropane-2-Sulfinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.