Description

(6-Hydroxypyrimidin-4-Yl)Acetic Acid is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its functionalized acetic acid moiety attached to a hydroxypyrimidine core, enabling its use in the development of novel active pharmaceutical ingredients and specialty chemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating new molecules with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require a pyrimidine backbone.
• Ligand and Chelator Development: Serves as a precursor for creating complexing agents and ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.
• Bioconjugation Chemistry: The carboxylic acid group facilitates its use in linking biomolecules or creating prodrugs in biopharmaceutical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity heterocyclic acids.

Basic Information

Item	Detail
Product Name	(6-Hydroxypyrimidin-4-Yl)Acetic Acid
CAS No.	1119449-91-0
Molecular Formula	C6H6N2O3
Molecular Weight	154.12 g/mol
Synonyms	4-(Carboxymethyl)-6-hydroxypyrimidine; 2-(6-Hydroxypyrimidin-4-yl)acetic acid; (6-Hydroxy-4-pyrimidinyl)acetic Acid; 4-Pyrimidineacetic acid, 6-hydroxy-; 6-Hydroxy-4-pyrimidineacetic acid
EINECS	Contact for details

Quality Control

Our (6-Hydroxypyrimidin-4-Yl)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.