Description

(3R)-1,2,3,4-Tetrahydroquinolin-3-Ol CAS NO 1119238-24-2 is a chiral, non-racemic organic compound belonging to the tetrahydroquinoline class, serving as a valuable and versatile synthetic building block. Its defined stereochemistry and functionalized core make it a critical intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in stereoselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(3R)-1,2,3,4-Tetrahydroquinolin-3-Ol
CAS No.	1119238-24-2
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(3R)-1,2,3,4-Tetrahydro-3-quinolinol; (R)-1,2,3,4-Tetrahydroquinolin-3-ol; (R)-3-Hydroxy-1,2,3,4-tetrahydroquinoline; (3R)-3-Hydroxy-1,2,3,4-tetrahydroquinoline; (R)-THQ-3-ol; 3-Quinolinol, 1,2,3,4-tetrahydro-, (3R)-; (R)-(-)-1,2,3,4-Tetrahydroquinolin-3-ol
EINECS	Contact for details

Quality Control

Our (3R)-1,2,3,4-Tetrahydroquinolin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination via HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full specification data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.