Description

Carbamic Acid, n-(6-Oxospiro[3.3]Hept-2-Yl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of next-generation small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compounds in drug discovery programs to explore new chemical space and improve drug-like properties.
• Process Chemistry & Scale-up: Employed in the development and optimization of robust, scalable synthetic routes for API manufacturing under cGMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and intermediate production.
• Academic Research: Utilized in university and institutional labs for studying novel organic reactions and synthesizing complex molecular frameworks.

Basic Information

Product Name	Carbamic Acid, n-(6-Oxospiro[3.3]Hept-2-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	1118786-86-9
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	tert-Butyl N-(6-oxospiro[3.3]heptan-2-yl)carbamate; 6-Oxospiro[3.3]heptane-2-carboxylic acid, 1,1-dimethylethyl ester; BOC-6-Oxospiro[3.3]hept-2-ylamine; N-Boc-6-oxospiro[3.3]heptan-2-amine; tert-Butyl (6-oxospiro[3.3]heptan-2-yl)carbamate; Spiro[3.3]heptane-6-one, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-; (6-Oxospiro[3.3]hept-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-(6-Oxospiro[3.3]Hept-2-Yl)-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.