Description

Ethyl 6-Fluoro-4-(Trifluoromethyl)Quinoline-2-Carboxylate is a high-value, multifunctional quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique trifluoromethyl and fluoro substituents make it an essential building block for creating compounds with enhanced biological activity and metabolic stability. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine and trifluoromethyl groups for improved efficacy and environmental profile.
• Material Science: Serves as a building block for functionalized organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Synthesis: Employed in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its versatile reactive sites.
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory research in heterocyclic and fluorine chemistry.

Basic Information

Product Name	Ethyl 6-Fluoro-4-(Trifluoromethyl)Quinoline-2-Carboxylate
CAS No.	1116339-58-2
Molecular Formula	C₁₃H₉F₄NO₂
Molecular Weight	287.21 g/mol
Synonyms	Ethyl 6-Fluoro-4-(trifluoromethyl)-2-quinolinecarboxylate; 2-Quinolinecarboxylic acid, 6-fluoro-4-(trifluoromethyl)-, ethyl ester; 6-Fluoro-4-(trifluoromethyl)quinoline-2-carboxylic acid ethyl ester; Ethyl 6-Fluoro-4-trifluoromethylquinoline-2-carboxylate; 1116339-58-2; Ethyl 6-Fluoro-4-(trifluoromethyl)quinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Fluoro-4-(Trifluoromethyl)Quinoline-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.