Description

2-Quinolinecarboxylic Acid, 4-(Trifluoromethyl)-, Hydrazide is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethyl-substituted quinoline core, which imparts desirable properties like enhanced metabolic stability and lipophilicity in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-infective research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, leveraging the bioactivity of the quinoline and trifluoromethyl groups.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its conjugated aromatic system.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	2-Quinolinecarboxylic Acid, 4-(Trifluoromethyl)-, Hydrazide
CAS No.	1116339-57-1
Molecular Formula	C11H8F3N3O
Molecular Weight	255.20 g/mol
Synonyms	4-(Trifluoromethyl)quinoline-2-carbohydrazide; 4-(Trifluoromethyl)-2-quinolinecarboxylic acid hydrazide; 2-Quinolinecarboxylic acid, 4-(trifluoromethyl)-, hydrazide; 4-Trifluoromethylquinoline-2-carboxylic acid hydrazide; 4-CF3-Quinoline-2-carbohydrazide; 1116339-57-1; 4-(Trifluoromethyl)-2-quinolylcarbohydrazide
EINECS	Contact for details

Quality Control

Our 2-Quinolinecarboxylic Acid, 4-(Trifluoromethyl)-, Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.