Description

2,4-Dichloro-5-Iodo-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique halogenated and sulfonated structure makes it a versatile precursor for constructing complex molecular architectures, particularly in pharmaceutical discovery. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting purine-binding sites.
• Agrochemical Research: Serves as a core scaffold for synthesizing novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe Development: Used to create tagged or modified probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential building block for organic electronic materials and advanced polymers due to its electron-deficient pyrrolopyrimidine core.
• Cross-Coupling Reactions: The iodine and chlorine substituents provide orthogonal sites for selective metal-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) to introduce diverse functional groups.
• Nucleoside Analogue Synthesis: Acts as a modified nucleobase analogue for creating novel antiviral or antimetabolite compounds.

Basic Information

Item	Detail
Product Name	2,4-Dichloro-5-Iodo-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1116240-01-7
Molecular Formula	C13H7Cl2IN3O2S
Molecular Weight	474.04 g/mol
Synonyms	7H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-5-iodo-7-[(4-methylphenyl)sulfonyl]-; 2,4-Dichloro-5-iodo-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine; 5-Iodo-2,4-dichloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine; 7-Tosyl-2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Iodo-7-Tosyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for advanced pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.