Description

7-Amino-3,4-Dihydro-6-Methoxy-2(1H)-Quinolinone is a high-purity, advanced pharmaceutical intermediate with a distinct quinolinone core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular pathways. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with quinoline-based structures.
• Neurological Research: Used in the development of compounds for central nervous system (CNS) disorders.
• Cardiovascular Drug Synthesis: Serves as a precursor for molecules targeting hypertension and other cardiovascular conditions.
• Chemical Biology Probes: Utilized in the creation of probes for studying enzyme mechanisms and receptor interactions.
• Organic Synthesis Research: Acts as a versatile starting material for heterocyclic chemistry and method development.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for cGMP-compliant API production.

Basic Information

Product Name	7-Amino-3,4-Dihydro-6-Methoxy-2(1H)-Quinolinone
CAS No.	1116232-42-8
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	6-Methoxy-7-amino-3,4-dihydro-2(1H)-quinolinone; 7-Amino-6-methoxy-3,4-dihydroquinolin-2(1H)-one; 2(1H)-Quinolinone, 7-amino-3,4-dihydro-6-methoxy-; 7-Amino-6-methoxy-1,2,3,4-tetrahydroquinolin-2-one; A-7832; AMQ; 7-ADMQ
EINECS	Contact for details

Quality Control

Our 7-Amino-3,4-Dihydro-6-Methoxy-2(1H)-Quinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.