Description

2-Oxo-1,2-Dihydro-Quinoline-7-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a versatile electrophile for introducing the sulfonamide or sulfonate functional group, enabling the development of novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its sulfonyl chloride reactivity.
• Material Science: Employed in the creation of functional polymers, dyes, and advanced organic materials requiring sulfonamide linkages.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Custom Synthesis & Contract Manufacturing: Serves as a fundamental building block for custom synthesis projects and scale-up production for specialized clients.

Basic Information

Product Name	2-Oxo-1,2-Dihydro-Quinoline-7-Sulfonyl Chloride
CAS No.	1116135-36-4
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	7-Quinolinesulfonyl chloride, 1,2-dihydro-2-oxo-; 2-Oxo-1,2-dihydroquinoline-7-sulfonyl chloride; 1,2-Dihydro-2-oxoquinoline-7-sulfonyl chloride; Quinolin-2(1H)-one-7-sulfonyl chloride; 7-Sulfonylchloride-2(1H)-quinolinone; 2-Hydroxyquinoline-7-sulfonyl chloride (tautomeric form); 7-Chlorosulfonyl-2-hydroxyquinoline; 2-Oxo-1,2-dihydro-7-quinolinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Oxo-1,2-Dihydro-Quinoline-7-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.