Description

Benzenamine, 3-Fluoro-4-(1H-Pyrazolo[3,4-B]Pyridin-4-Yloxy)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it serves as a critical building block for developing targeted therapies, particularly in oncology and other disease areas requiring precise molecular intervention. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its role in constructing complex heterocyclic scaffolds with potential kinase inhibitory activity.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Oncology Research: Used in the discovery and development of targeted cancer therapies due to its specific heterocyclic structure.
• Chemical Biology Probes: Serves as a core structure for creating tool compounds to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry programs and novel synthetic methodology development.
• Process Chemistry Optimization: Employed in scaling up synthetic routes from milligram to kilogram scale for clinical trial material production.

Basic Information

Product Name	Benzenamine, 3-Fluoro-4-(1H-Pyrazolo[3,4-B]Pyridin-4-Yloxy)-
CAS No.	1115490-85-1
Molecular Formula	C12H9FN4O
Molecular Weight	244.23 g/mol
Synonyms	3-Fluoro-4-((1H-pyrazolo[3,4-b]pyridin-4-yl)oxy)aniline; 4-((1H-Pyrazolo[3,4-b]pyridin-4-yl)oxy)-3-fluoro-benzenamine; 3-Fluoro-4-(1H-pyrazolo[3,4-b]pyridin-4-yloxy)phenylamine; 3-Fluoro-4-(1H-pyrazolo[3,4-b]pyridin-4-yloxy)aniline; Aniline, 3-fluoro-4-((1H-pyrazolo[3,4-b]pyridin-4-yl)oxy)-; 1115490-85-1; 3-Fluoro-4-(1H-pyrazolo[3,4-b]pyridin-4-yloxy)benzenamine
EINECS	Contact for details

Quality Control

Our Benzenamine, 3-Fluoro-4-(1H-Pyrazolo[3,4-B]Pyridin-4-Yloxy)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and process development. Certificates of Analysis (COA) with full traceability are provided for each lot, and we support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.