Description

R-2-Isobutyl-1,2,3,4-Tetrahydro-Quinoline is a chiral tetrahydroquinoline derivative, a versatile intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry is crucial for biological activity. It is needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel, high-value compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific stereochemistry influences efficacy.
• Catalyst and Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new chemical spaces.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and advanced polymers.

Basic Information

Product Name	R-2-Isobutyl-1,2,3,4-Tetrahydro-Quinoline
CAS No.	1115387-00-2
Molecular Formula	C₁₃H₁₉N
Molecular Weight	189.30 g/mol
Synonyms	(R)-2-Isobutyl-1,2,3,4-tetrahydroquinoline; (R)-2-(2-Methylpropyl)-1,2,3,4-tetrahydroquinoline; R-2-Isobutyl-THQ; (R)-IBTHQ; (2R)-2-(2-Methylpropyl)-1,2,3,4-tetrahydroquinoline; Tetrahydroquinoline, 2-isobutyl-, (R)-; 1,2,3,4-Tetrahydro-2-isobutylquinoline, (R)-
EINECS	Contact for details

Quality Control

Our R-2-Isobutyl-1,2,3,4-Tetrahydro-Quinoline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.