Description

2H-Imidazol-2-Imine, 1-[(6-Chloro-3-Pyridinyl)Methyl]-1,3-Dihydro-n-Nitro-, (2E)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutic agents. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for its role as a key building block in organic synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of new drug candidates, especially those targeting neurological or infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing next-generation pesticides and insecticides, leveraging its chloropyridine and imidazole motifs.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and receptor-ligand interactions due to its specific molecular architecture.
• Organic Synthesis Building Block: Employed in complex organic transformations to introduce functionalized imidazole and pyridine rings into larger molecules.
• Material Science Research: Investigated as a potential monomer or ligand for creating functional polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	2H-Imidazol-2-Imine, 1-[(6-Chloro-3-Pyridinyl)Methyl]-1,3-Dihydro-n-Nitro-, (2E)-
CAS No.	1115248-04-8
Molecular Formula	C9H8ClN5O2
Molecular Weight	253.65 g/mol
Synonyms	(2E)-1-[(6-Chloropyridin-3-yl)methyl]-1,3-dihydro-2H-imidazol-2-imine N-oxide; 1-((6-Chloropyridin-3-yl)methyl)-1,3-dihydro-2H-imidazol-2-imine N-oxide (2E); 2H-Imidazol-2-imine, 1-[(6-chloro-3-pyridinyl)methyl]-1,3-dihydro-N-nitro-, (2E)-; 1115248-04-8; (E)-1-((6-Chloropyridin-3-yl)methyl)-1,3-dihydro-2H-imidazol-2-imine N-oxide
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems to ensure consistency and traceability. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical starting materials, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids/bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.