Description

(S)-5-Fluoro-2,3-Dihydro-1H-Inden-1-Amine-Hcl CAS NO 1114333-11-7 is a high-purity chiral amine hydrochloride salt, a key building block in advanced pharmaceutical synthesis. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules where the (S)-enantiomer configuration is essential for biological activity.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with specific stereochemical requirements.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Asymmetric Catalysis: Can be utilized as a chiral ligand precursor or auxiliary in catalytic reactions to induce enantioselectivity.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(S)-5-Fluoro-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	1114333-11-7
Molecular Formula	C9H11ClFN
Molecular Weight	187.64 g/mol
Synonyms	(1S)-5-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride; (S)-5-Fluoroindan-1-amine hydrochloride; (S)-1-Amino-5-fluoroindane HCl; (S)-5-Fluoro-1-indanamine hydrochloride; 5-Fluoro-(1S)-indan-1-amine hydrochloride; (S)-5-Fluoro-2,3-dihydro-1H-inden-1-amine HCl; (1S)-5-Fluoroindan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-5-Fluoro-2,3-Dihydro-1H-Inden-1-Amine-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.