Description

(1S,3S)-1-(Hydroxymethyl)-3-(Tritylamino)Cyclopentanol CAS NO 1113025-25-4 is a high-purity, chiral cyclopentanol derivative featuring both hydroxymethyl and trityl-protected amino functional groups. This compound is a critical advanced pharmaceutical intermediate (API intermediate) valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, or neurological drugs.
• Asymmetric Synthesis: Used in stereoselective chemical reactions to introduce specific chiral centers into target molecules.
• Peptidomimetics & Prodrug Development: Serves as a scaffold for creating peptide mimics or designing prodrugs due to its protected amine and alcohol functionalities.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies during drug discovery.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high chiral purity.

Basic Information

Product Name	(1S,3S)-1-(Hydroxymethyl)-3-(Tritylamino)Cyclopentanol
CAS No.	1113025-25-4
Molecular Formula	C25H27NO2
Molecular Weight	373.49 g/mol
Synonyms	(1S,3S)-1-(Hydroxymethyl)-3-(triphenylmethylamino)cyclopentanol; (1S,3S)-3-[(Triphenylmethyl)amino]-1-(hydroxymethyl)cyclopentanol; 1-(Hydroxymethyl)-3-(tritylamino)cyclopentanol, (1S,3S)-; (1S,3S)-1-(Hydroxymethyl)-3-(tritylamino)cyclopentan-1-ol; Trityl-protected amino cyclopentanol derivative; (1S,3S)-3-(Tritylamino)-1-(hydroxymethyl)cyclopentanol
EINECS	Contact for details

Quality Control

Our (1S,3S)-1-(Hydroxymethyl)-3-(Tritylamino)Cyclopentanol is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.