Description

4-(Thien-2-Ylmethyl)Benzylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its unique thienyl-benzylamine scaffold.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides that require specific heterocyclic amine structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	4-(Thien-2-Ylmethyl)Benzylamine Hydrochloride
CAS No.	1112459-82-1
Molecular Formula	C12H14ClNS
Molecular Weight	239.76 g/mol
Synonyms	4-[(Thiophen-2-ylmethyl)]benzylamine hydrochloride; 1-[4-(Thiophen-2-ylmethyl)phenyl]methanamine hydrochloride; 4-(2-Thienylmethyl)benzylamine HCl; Benzenemethanamine, 4-[(2-thienylmethyl)]-, hydrochloride; 4-(Thien-2-ylmethyl)benzylamine HCl; 4-(Thiophen-2-ylmethyl)benzylamine hydrochloride; (4-((Thiophen-2-yl)methyl)phenyl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Thien-2-Ylmethyl)Benzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets stringent research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.