Description

4-Fluoro-6-Trifluoromethyl-Nicotinic Acid is a high-value, multi-functional fluorinated pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Chemical Research (R&D): A versatile scaffold for medicinal chemistry and discovery chemistry programs, enabling structure-activity relationship (SAR) studies.
• Fluorinated Compound Library: Used in the construction of screening libraries for high-throughput testing in drug and agrochemical discovery.
• Material Science Precursor: Potential intermediate in the synthesis of fluorinated polymers or specialty materials with unique properties.

Basic Information

Product Name	4-Fluoro-6-Trifluoromethyl-Nicotinic Acid
CAS No.	1105988-64-4
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	4-Fluoro-6-(trifluoromethyl)nicotinic acid; 4-Fluoro-6-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-fluoro-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-4-fluoronicotinic acid; 4-Fluoro-6-trifluoromethylpyridine-3-carboxylic acid; 4-Fluoro-6-trifluoromethyl-3-pyridinecarboxylic acid; 1105988-64-4; 4-Fluoro-6-trifluoromethylnicotinic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-6-Trifluoromethyl-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced intermediate use. Certificates of Analysis (COA) are provided with every shipment, detailing key parameters such as assay, purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.