Description

4',5-Di-o-Acetyl Genistein 7-(Tri-o-Acetyl-β-D-Glucuronic Acid Methyl Ester) is a chemically modified derivative of the isoflavone genistein, designed for enhanced stability and bioavailability in advanced research and development. This compound serves as a crucial synthetic intermediate for producing more soluble and bioavailable forms of genistein, a molecule of significant interest for its biological activity. It is primarily utilized by pharmaceutical, nutraceutical, and life science research organizations focused on developing novel therapeutics, standardized botanical extracts, and high-purity reference standards.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting hormone-related pathways and oxidative stress.
• Reference Standard: High-purity compound for analytical method development, validation, and quality control in laboratories.
• Nutraceutical R&D: Used in research to develop advanced, standardized botanical supplements with improved pharmacokinetic profiles.
• Biochemical Research: Probe for studying the structure-activity relationships (SAR) of flavonoid glycosides and their metabolites.
• Metabolite Synthesis: Intermediate for the preparation of glucuronidated metabolites for pharmacological and toxicological studies.

Basic Information

Product Name	4',5-Di-o-Acetyl Genistein 7-(Tri-o-Acetyl-β-D-Glucuronic Acid Methyl Ester)
CAS No.	1105697-83-3
Molecular Formula	C34H34O17
Molecular Weight	714.63 g/mol
Synonyms	Genistein 4',5-Diacetate 7-(Tri-O-acetyl-β-D-glucopyranuronate) Methyl Ester; Methyl (2S,3S,4S,5R,6S)-3,4,5-triacetoxy-6-((5-acetoxy-7-(4-acetoxyphenyl)-4-oxo-4H-chromen-3-yl)oxy)oxane-2-carboxylate; 4',5-Di-O-acetylgenistein 7-O-(tri-O-acetyl-β-D-glucopyranuronosyl) Methyl Ester; Acetylated Genistein Glucuronide Methyl Ester; Genistein-7-glucuronide peracetate methyl ester
EINECS	Contact for details

Quality Control

Our 4',5-Di-o-Acetyl Genistein 7-(Tri-o-Acetyl-β-D-Glucuronic Acid Methyl Ester) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects requiring material that meets in-house specifications for pharmaceutical intermediates and analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.