Description

4-Azaspiro[2.5]Octane-5,7-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a critical scaffold for constructing spirocyclic and fused heterocyclic compounds in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and development stages for creating potential new APIs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: Employed in synthetic organic chemistry research to explore new reaction methodologies and compound libraries.

Basic Information

Product Name	4-Azaspiro[2.5]Octane-5,7-Dione
CAS No.	1105663-34-0
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	4-Azaspiro[2.5]octane-5,7-dione; 5,7-Dioxo-4-azaspiro[2.5]octane; 4-Azaspiro[2.5]octane-5,7-dione; 1-Azaspiro[2.5]octane-2,4-dione (tautomer); Spiro[2.5]octane-1,3-dione, 4-aza-; 4-Aza-1-oxaspiro[2.5]octane-2,8-dione (alternative representation); 1105663-34-0 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Azaspiro[2.5]Octane-5,7-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.