Description

2-(4-Methylpiperazine-1-Carbonyl)-1,2,3,4-Tetrahydroquinoline is a high-purity advanced pharmaceutical intermediate (API) with significant synthetic utility. This compound is valued for its role as a key building block in the research and development of novel bioactive molecules, particularly in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules and investigational new chemical entities.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS-Active Compound Synthesis: Used in the development of compounds targeting neurological receptors and pathways, owing to its tetrahydroquinoline and piperazine motifs.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis services catering to the pharmaceutical and biotechnology industries.
• Academic & Institutional Research: Employed in university and institutional labs for chemical biology studies and the development of new synthetic methodologies.

Basic Information

Product Name	2-(4-Methylpiperazine-1-Carbonyl)-1,2,3,4-Tetrahydroquinoline
CAS No.	1104561-97-8
Molecular Formula	C15H21N3O
Molecular Weight	259.35 g/mol
Synonyms	1,2,3,4-Tetrahydro-2-[(4-methyl-1-piperazinyl)carbonyl]quinoline; 2-(4-Methylpiperazine-1-carbonyl)-1,2,3,4-tetrahydroquinoline; 2-(4-Methylpiperazine-1-carbonyl)-1,2,3,4-tetrahydro-quinoline; 2-(4-Methylpiperazine-1-carbonyl)tetrahydroquinoline; 2-[(4-Methylpiperazin-1-yl)carbonyl]-1,2,3,4-tetrahydroquinoline; 1104561-97-8; 2-(4-Methyl-1-piperazinylcarbonyl)-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazine-1-Carbonyl)-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs and can provide material suitable for research and development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.