Description

1-(Bromomethyl)-3-Fluoro-2-Nitrobenzene is a versatile and high-value halogenated aromatic building block, essential for advanced organic synthesis. Its molecular structure, featuring reactive bromomethyl and nitro groups adjacent to a fluorine atom, makes it a critical intermediate for constructing complex molecules with precise functionality. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules due to the reactivity of the bromomethyl group.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a fluoronitrophenyl moiety.

Basic Information

Product Name	1-(Bromomethyl)-3-Fluoro-2-Nitrobenzene
CAS No.	1104543-73-8
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	3-Fluoro-2-nitrobenzyl bromide; 2-Nitro-3-fluorobenzyl bromide; (3-Fluoro-2-nitrophenyl)methyl bromide; 1-(Bromomethyl)-3-fluoro-2-nitrobenzene; α-Bromo-3-fluoro-2-nitrotoluene; Benzene, 1-(bromomethyl)-3-fluoro-2-nitro-; Bromomethyl-3-fluoro-2-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-3-Fluoro-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.