Description

4-Hydroxy-1-Methyl-3-(1-Methyl-1H-Benzimidazol-2-Yl)-2(1H)-Quinolinone is a high-value, complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique fused-ring structure, combining quinolinone and benzimidazole moieties, makes it a versatile building block for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its role in creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition, anti-cancer, and anti-inflammatory pathways.
• Agrochemical Research: Used as a core scaffold for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other advanced electronic materials due to its conjugated system.
• Biochemical Probe Development: Utilized in medicinal chemistry to create fluorescent probes or molecular tags for studying biological processes and enzyme activity.
• Organic Synthesis Research: A valuable substrate for methodological studies in cross-coupling, cyclization, and other complex organic transformations in academic and industrial R&D.

Basic Information

Product Name	4-Hydroxy-1-Methyl-3-(1-Methyl-1H-Benzimidazol-2-Yl)-2(1H)-Quinolinone
CAS No.	1104466-39-8
Molecular Formula	C18H15N3O2
Molecular Weight	305.33 g/mol
Synonyms	1-Methyl-3-(1-methyl-1H-benzimidazol-2-yl)-4-hydroxy-2(1H)-quinolinone; 4-Hydroxy-1-methyl-3-(1-methylbenzimidazol-2-yl)quinolin-2(1H)-one; 2(1H)-Quinolinone, 4-hydroxy-1-methyl-3-(1-methyl-1H-benzimidazol-2-yl)-; 1104466-39-8; UNII-9F2Z2I8V4C; 9F2Z2I8V4C; SCHEMBL21806227; DTXSID90648669
EINECS	Contact for details

Quality Control

Our production of 4-Hydroxy-1-Methyl-3-(1-Methyl-1H-Benzimidazol-2-Yl)-2(1H)-Quinolinone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.