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2,4-Difluoro-6-Methoxybenzoic Acid CAS NO 1104386-44-8
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CAS No.:1104386-44-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,4-Difluoro-6-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.
Application
- Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics where fluorine substitution is crucial.
- Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atoms to enhance biological activity and environmental persistence.
- Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies, where its structure aids in tuning molecular polarity and alignment.
- Organic Electronic Materials: Employed in the development of novel organic semiconductors and electron-transport materials due to its electron-withdrawing characteristics.
- Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex, polyfunctional aromatic scaffolds in academic and industrial labs.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in proprietary client synthesis projects requiring high-purity fluorinated intermediates.
Basic Information
| Product Name | 2,4-Difluoro-6-Methoxybenzoic Acid |
| CAS No. | 1104386-44-8 |
| Molecular Formula | C8H6F2O3 |
| Molecular Weight | 188.13 g/mol |
| Synonyms | 6-Methoxy-2,4-difluorobenzoic Acid; 2,4-Difluoro-6-methoxybenzoic Acid; Benzoic acid, 2,4-difluoro-6-methoxy-; 2,4-Difluoro-6-methoxy-benzoic acid; 1104386-44-8; 2,4-Difluoro-6-methoxybenzoicacid; AKOS040759623; SCHEMBL21807727 |
| EINECS | Contact for details |
Quality Control
Our 2,4-Difluoro-6-Methoxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | < 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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